A study in the Journal of the American Medical Association indicates that ubrogepant demonstrated greater rates of pain and symptom relief from migraine compared with a placebo. More than 20% of participants in a large-scale clinical trial reported being pain-free within 2 hours and more than 34% were relieved of the most severe symptoms associated with migraines when administered the drug, compared with 14% and 27%, respectively, from the placebo. These symptoms include light and noise sensitivity. Richard B. Lipton, MD, director of the Montefiore Headache Center in New York, who led the study, observes: “Migraine is the second leading cause of disability, and we need new acute treatments that are efficacious, safe, and tolerable.” Lipton is a consultant for Allergan, the pharmaceutical company that sponsored the trial. Ubrogepant is currently pending approval by the FDA. The drug targets a protein called calcitonin gene-related peptide, which is involved in the transmission of pain.
- CGRP QUESTIONS/ANSWERS
- New Butalbital Product(similar to Fioricet/Fiorinal/Esgic/Phrenilin)
- CGRP Migraine Monoclonal Injections: proceed with caution" from Dr. Robbins, M.D.
- "What Can Cause Stomach Pain and a Headache?" from Medical News Today
- CGRP AND SIDE EFFECTS: LETTER IN ‘HEADACHE”
- "The Truth About White (And Pink And Brown) Noise For Sleep" from CNN Health
- "People With Migraine Really Are Affected By The Weather" from MigraineAgain
- "Terrell Davis Recalls How A Debilitating Migraine Almost Took Him Out of Super Bowl XXXII" from People magazine
adolescents Alzheimer's disease Alzheimers anxiety back pain blood pressure botox brain caffeine children chronic migraine chronic pain cluster headache concussion concussions COVID-19 dementia depression diet exercise fibromyalgia Headache headache blog headaches health heart disease meditation migraine migraine headache migraine headaches migraines migraine triggers migraine with aura pain Pandemic physical activity sleep stress stroke triggers triptans vitamin D walking women yoga