According to lead researcher Amy Gelfand, MD, assistant professor, Clinical Neurology and Pediatrics, University of California, San Francisco, and child neurologist University of California, San Francisco, Headache Center, the results of a new meta-analysis linking the 2 conditions suggest that “colic is an age-sensitive phenotype of migraine.”

Dr. Gelfand believes it may be time to bring colic into the main body of the International Classification of Headache Disorders (ICHD) document from the appendix, where it’s now an “episodic syndrome that may be associated with migraine.”

She says that better understanding of the link between infant colic and migraine could help to put to rest the often-repeated theory that colic has something to do with feeding and gastrointestinal disorders.

She presented results of the new analysis at the American Headache Society 56th Annual Scientific Meeting.

The primary analysis included 3 studies with a total of 891 participants. One of these studies was conducted by Dr. Gelfand and colleagues. In it, the researchers analyzed 154 surveys and found that infants whose moms had migraine were 2.6 times more likely to have colic.

Another study found that children or adolescents with migraine were 6.6 times more likely to have had infantile colic than those without migraine; a third article included 58 participants and found a similar connection……     7/3/14

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