Home | About Dr. Robbins | Archived Articles | Headache Books | Topic Index | Links |
Title: |
Epidemiology, Risk Factors, and Treatment of |
|
The term chronic daily headache refers to a
heterogeneous group of headache disorders characterized by a
frequency of headaches on ≥ 15 days per month. Chronic
migraine is a subtype of chronic daily headache. The prevalence of
chronic migraine is ~ 1%. Baseline attack frequency and acute
medication overuse have been identified as potential risk factors
for the progression of migraine from an episodic disorder to a
chronic condition. There is an unmet patient need for effective
and safe treatments for patients with chronic migraine, but data
from rigorous controlled trials are limited. Previous studies have
demonstrated that topiramate is an effective and safe preventive
treatment for episodic migraine. In addition, pilot studies have
suggested the utility of topiramate for the prevention of chronic
migraine. Two randomized, double-blind, placebo-controlled,
multicenter trials investigating the efficacy and safety of topiramate
in the treatment of patients with chronic migraine have recently been
completed. This review presents comparative data from these 2 clinic
trials, which suggest that topiramate at a dose of 100 mg. daily is
effective and generally well tolerated in chronic migraine.
|
Home | About Dr. Robbins | Archived Articles | Headache Books | Topic Index | Links
Copyright © 2002- Lawrence Robbins, MD
All Rights Reserved.
This site is maintained by MICE Training & Technology™ Web Design
Contact: