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Analgesic Outcomes in Patients with Painful
Diabetic Neruopathy or Post-herpetic Neuralgia
Receiving Pregabalin v. Gabapentin
M. Vera-Llonch, E. Dukes, C. Argoff, G. Oster
Posted: September 2005  
Journal of Pain, Vol. 6, March 2005

This study’s aim was to estimate analgesic outcomes in patients with painful diabetic peripheral neuropathy (DPN) or post-herpetic neuralgia (PHN) receiving Pregabalin versus gabapentin. We developed a stochastic stimulation model to estimate the impact on analgesic outcomes of treatment with Pregabalin (375 mg. per day) versus gabapentin (1200 mg. and 1800 mg. per day) in a hypothetical cohort of 1,000 patients with DPN or PHN.

In patients with DPN or PHN, pregabalin may provide better analgesic outcomes than gabapentin over a 12-week period.