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Migraine is Associated with Menorrhagia and
Endometriosis
Tietjen G.D., et al.
Posted August 2003
Presented at: 45th Annual Scientific Meeting
American Headache Society

June 19-22, 2003; Chicago, Illinois


Objectives: To evaluate the frequency of menorrhagia and endometriosis in female migraineurs compared to age-matched controls.

Conclusions: Migraineurs have a higher frequency of endometriosis, menorrhagia, and associated psychosocial consequences. These findings suggest that in the female migraine population there should be further study of factors (e.g., eicosanoids, platelet function) which influence endometriosis and menstrual blood flow. The findings of menorrhagia, increased bruising, and rectal bleeding are intriguing given the fact that in women of childbearing age migraine is reported to be an ischemic stroke risk factor, and hypercoagulability has been suspected.