Comparison with intravenous dihydroergotamine (DHE)


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Repetitive intravenous administration of valproate
sodium in intractable migraine:
comparison with intravenous dihydroergotamine (DHE)
N.T. Mathew
Posted Nov 2000
Cephalalgia, May 2000

Objective:
To evaluate the efficacy and tolerability of repetitive intravenous (IV) valproate sodium (Depacon™) in intractable migraine and compare it with IV DHE.

Conclusion: Repetitive IV valproate sodium and IV DHE are equally effective in breaking the cycle of intractable migraine and the former is associated with significantly fewer adverse events.

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